Quiz 4 Unit 4 Viruses (25 points)

Part A. Multiple Choice and Fill in the Blank (1 point each)
1. Which of the
following explains why viruses are only able to multiply in living cells?
a. Viruses
are too small to multiply outside of living cells.
b. Viruses
do not have the necessary components for self-replication
c. Their binary
fission is controlled by host cell genes
d. All of
the above
2. Retroviruses are
named because their reverse transcriptase
a. reverses the action of drugs on viruses.
b. reverses the ability of viruses to associate with cells.
c. reverses the response to antibiotics.
d. reverses the flow of genetic information from RNA to DNA.
e. all of the above.
3. Which of the
following structures is responsible for the changes in influenza viruses that
requires the development of a new vaccine each season?
a. Changes in the envelope phospholipids
b. Changes in the surface spike proteins
c. Changes in the internal capsid proteins
d. Changes in the RNA genome
e. All of the above
4. The release of the viral genome from the capsid is called
a. Endocytosis
b. Uncoating
c. Penetration
d. Biosynthesis
e. Maturation
5. How can an
individual end up with spongiform disease?
e. a. Eating
meat with PrPSc (infectious PrP-res)
f. b.
Inherited a mutation in the gene coding for PrPc (PrP-sen)
g. c. A
spontaneous mutation that changes the PrPc form to the PrPSc form
h. d. All of
the above
Part B. Short Answers (4 points each)
Answer the questions below as completely and as thoroughly
as possible and where appropriate include a specific example to illustrate.
Answer the questions in essay form (not as an outline or bullets) using
complete sentences. You may use a diagram or table to supplement your answers,
but a diagram or table alone without appropriate discussion will not be
adequate for full credit.
Reminder: All answers must be written in your own words and
include complete and accurate citations for the sources you used or that
support your answer. No points will be earned for answers without citations or
with incorrect citations. Citations for the course modules must include the
section topic.
6. How do viruses cause disease (the effect(s) on host cells
or tissues that cause disease)? Name a specific virus and the disease it causes
and how it causes the disease. This is not about the stages of the virus life
cycle.
7. What are the
mechanisms by which mature enveloped and non-enveloped viruses enter and leave
a host cell? Briefly describe the processes and name an animal virus for each.
8. Name the
structural components common to viruses and describe the function of each.
Describe at least three structural characteristics that contribute to the high
diversity in types of animal viruses and give examples to illustrate the
differences.
9. Describe the steps
from viral attachment to the host cells and translation of the HIV genome in
the host cell and the role of the viral enzyme reverse transcriptase in the
process. Include the names of the stages of the life (replication) cycle.
10. State the normal function of proto-oncogenes, and
describe how some viruses may contribute to the development of tumors by
altering proto-oncogenes. Name two oncogenic viruses and the type of cancer
they cause.
Quiz 4 Unit 4 Viruses (25 points)Part A. Multiple Choice and Fill in the Blank (1 point each)1. Which of the
following explains why viruses are only able to multiply in living cells?a. Viruses
are too small to multiply outside of living cells.b. Viruses
do not have the necessary components for self-replicationc. Their binary
fission is controlled by host cell genesd. All of
the above2. Retroviruses are
named because their reverse transcriptasea. reverses the action of drugs on viruses.b. reverses the ability of viruses to associate with cells.c. reverses the response to antibiotics.d. reverses the flow of genetic information from RNA to DNA.e. all of the above.3. Which of the
following structures is responsible for the changes in influenza viruses that
requires the development of a new vaccine each season?a. Changes in the envelope phospholipidsb. Changes in the surface spike proteinsc. Changes in the internal capsid proteinsd. Changes in the RNA genomee. All of the above4. The release of the viral genome from the capsid is calleda. Endocytosisb. Uncoatingc. Penetrationd. Biosynthesise. Maturation5. How can an
individual end up with spongiform disease? e. a. Eating
meat with PrPSc (infectious PrP-res)f. b.
Inherited a mutation in the gene coding for PrPc (PrP-sen)g. c. A
spontaneous mutation that changes the PrPc form to the PrPSc formh. d. All of
the abovePart B. Short Answers (4 points each)Answer the questions below as completely and as thoroughly
as possible and where appropriate include a specific example to illustrate.
Answer the questions in essay form (not as an outline or bullets) using
complete sentences. You may use a diagram or table to supplement your answers,
but a diagram or table alone without appropriate discussion will not be
adequate for full credit. Reminder: All answers must be written in your own words and
include complete and accurate citations for the sources you used or that
support your answer. No points will be earned for answers without citations or
with incorrect citations. Citations for the course modules must include the
section topic.6. How do viruses cause disease (the effect(s) on host cells
or tissues that cause disease)? Name a specific virus and the disease it causes
and how it causes the disease. This is not about the stages of the virus life
cycle.7. What are the
mechanisms by which mature enveloped and non-enveloped viruses enter and leave
a host cell? Briefly describe the processes and name an animal virus for each. 8. Name the
structural components common to viruses and describe the function of each.
Describe at least three structural characteristics that contribute to the high
diversity in types of animal viruses and give examples to illustrate the
differences.9. Describe the steps
from viral attachment to the host cells and translation of the HIV genome in
the host cell and the role of the viral enzyme reverse transcriptase in the
process. Include the names of the stages of the life (replication) cycle.10. State the normal function of proto-oncogenes, and
describe how some viruses may contribute to the development of tumors by
altering proto-oncogenes. Name two oncogenic viruses and the type of cancer
they cause.

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